Healing Properties of Adipose Derived Stem Cells

submitted by Spa Blue

6735 Conroy-Windermere Rd., Suite 423

Orlando • 407-772-2583


Damage to the body typically results in inflammation. This could be in the form of redness, raised or bumpy skin, blisters, rashes, itching, burning, etc. This is the body’s natural reaction; it is part of an automatic immune response to identify and assess the extent of the damage, to stop any bleeding or immediate threat to the body (such as infection), and ultimately to heal and repair the damage caused to restore proper function.

adipose derived stem cells

Adipose Derived Stem Cells

While some inflammation is a normal and necessary part of the immune system doing its job, chronic inflammation or an over-reaction of the immune system, such as in an allergic reaction, is not beneficial. So the goal is to limit and control inflammation while boosting the positive effects of healing and repair that follow.

It is with this in mind that microdermabrasion, microneedling, laser resurfacing, chemical peels and other minimally invasive, inflammation-inducing procedures have been developed. The goal is to “trick” the body into mobilizing its stem cell populations, producing healing factors and inducing natural healing in a specific area of the body for aesthetic improvement.

What is the best way to boost healing and control inflammation? When tested in vitro and in human clinical trials, adipose derived stem cells (ADSCs) and the proteins derived from them have consistently been shown to decrease and control inflammation while guiding and improving healing. This is why ADSCs are often the stem cell type of choice for wound healing and skin remodeling, as well as serious autoimmune- and inflammation-related diseases and disorders, including Crohn’s disease, radiation-induced fibrosis, ulcerative colitis, allergic airway inflammation, autoimmune arthritis, inflammatory bowel disease and lupus dermatitis.

ADSCs are a type of mesenchyal stem cell, or MSC, that exist within the fat tissue just under the dermis in a layer called the hypodermis. When the skin is injured, these cells just below the dermis are the first responders. They orchestrate healing and are capable of turning into all of the cell types that compose human skin. Other sources of MSCs include, but are not limited to, liposuction aspirate (fat), bone marrow aspirate, umbilical cord blood and placenta.

The healing properties of ADSCs and the proteins they produce have been extensively studied, particularly in regards to the skin. All properly isolated and cultured MSCs, regardless of source, produce remarkably similar protein profiles. This means that the cytokines, growth factors, immunomodulatory factors, anti-inflammatory proteins and other signaling molecules produced by MSCs from different source tissues, such as bone marrow, adipose tissue or umbilical cord blood, are more or less the same.

In fact, the main differences between the quality and amount of proteins produced by MSCs that are captured for topical use has a lot to do with the technical expertise of the scientists culturing the cells. Differences in cell isolation, cell culture conditions, protein purification, formulation and delivery method can greatly affect the quality of the final product.

Stem cell growth factors fight against inflammation and redness, and improve texture, pigmentation problems, sunspots, melasma and wrinkles. It has even been shown to shrink pores. Amazing new technology is now available as a serum for daily use and as a stem cell facial at select spas. 💓

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